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MEDICAL ERROR

DrugFreeAmerica.jpg (66049 bytes)We estimated that in 1994 overall 2,216,000 hospitalized patients had serious adverse drug reactions.  Serious adverse drug reactions were defined as those that resulted in death, were permanently disabling, or required hospitalization.  We estimated that 106,000 had fatal adverse drug reactions, making these reactions between the fourth and sixth leading cause of death. We excluded errors in drug administration, noncompliance, overdose, drug abuse, therapeutic failures, and possible adverse drug reactions. The incidence of serious and fatal adverse drug reactions in U.S. hospitals was found to be extremely high! According to author Bruce H. Pomeranz, only 156 death certificates showed deaths due to drug reactions. Even when the cause is known to be a drug, that is rarely recorded on the death certificate. A certificate might list a stomach hemorrhage as the cause of death, without mentioning the use of the drug that brought it on.  10.

Therapeutic drug use (not illicit drug use) each year; kills as many as 198,815 people, puts 8.8 million people in hospitals, accounts for 28% of all hospital admissions, and costs as much as $182 billion dollars.  4.

The Lancet states that medication-error deaths are rising and reports that one out of every 131 outpatient deaths were caused by medication error and goes on to state that "patients must understand that and be warned about the potential dangers of prescription drugs." 11.

Medical malpractice is the 3rd leading cause of preventable death in the United States. Malpractice is responsible for the deaths of 80,000 people annually, one every 7 minutes. This does not include iatrogenic injury. 2.

180,000 people die each year partly as a result of iatrogenic injury. The equivalent of three jumbo jet crashes every 2 days.
    64 % of cardiac arrests at a teaching hospital were preventable. Most were due to use of medications.      
    36 % of those admitted to a teaching hospital suffered an iatrogenic event, 25% of which were serious or life threatening.
    20% of all patients admitted to a university hospital suffered iatrogenic injury. 3.

Of 1,047 patients during the study. Adverse events were identified by healthcare personnel in 480 patients, of which 185 resulted in serious complications ranging from temporary disability to death.
     45% of patients suffered inappropriate care resulting in complications or medical injury caused by a hospital staff member
    17.7% had at least one serious adverse event
    37.8% of adverse events were caused by an individual
    17.7% of patients experienced serious events that led to longer hospital stays and increased costs to the patients
    The likelihood of experiencing an adverse event increased about 6% for each day of hospital stay.  5.

"Only about 15% of all medical interventions are supported by scientific evidence. This is partly because only 1% of the articles written in medical journals are scientifically sound." D. Eddy, M.D., Ph.D. 1.

Drug errors not only increase costs, but also significantly prolong hospital stays and increase the risk of death almost 2-fold. 7.

Preventable drug-related morbidity and mortality was estimated to cost $76.6 billion in the ambulatory setting in the United States. The largest component of this total cost was associated with drug-related hospitalizations. The estimated cost ranged from a conservative estimate of $30.1 to $136.8 billion in a worst-case scenario. 9.

We estimated that the annual additional costs associated with preventable [adverse drug events] were $2.8 million and that the costs associated with all [adverse drug events] were $5.6 million. 6.

Several easily identifiable factors are associated with a large proportion of medical prescribing errors. Factors commonly associated with errors in prescribing medications were inadequate knowledge or use of knowledge regarding drug therapy; presence of important patient factors related to drug therapy such as age, impaired renal function, and drug allergy; the need for calculation of drug doses; and specialized dosage formulation characteristics and medication prescribing nomenclature. Adverse drug events in hospitalized patients are "...countable, dangerous and evaluable events, not just a collection of unhappy accidents that strike, like cosmic rays, in ways that we cannot predict or understand. In an era of constrained resources, it is vital to remember that [drug errors] in hospitals are common, costly and preventable in many cases."  8.

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© 1996-2003 Craig M. Anderson, D.C.